Developing Heterologous Expression Platforms for the Production of Polyketides from Microbial Hosts
Bacterial polyketides possess an enormous range of chemical diversity and biological function. Many polyketides such as tetracycline, epothilone, and rapamycin have been developed into key clinical pharmaceuticals in a broad range of therapeutic areas. Sequencing of bacterial genomes has shown that...
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| Language: | en |
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Université d'Ottawa / University of Ottawa
2011
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| Online Access: | http://hdl.handle.net/10393/20220 http://dx.doi.org/10.20381/ruor-4816 |