ABCA1 Increases Extracellular ATP to Mediate Cholesterol Efflux to ApoA-I

ABCA1 is a key plasma membrane protein required for the efflux of cellular cholesterol to extracellular acceptors, particularly to apoA-I. This process is essential to maintain cholesterol homeostasis in the body. The detailed molecular mechanisms, however, are still insufficiently understood. Also,...

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Bibliographic Details
Main Author: Lee, Jee Yeon
Other Authors: Zha, Xiaohui
Language:en
Published: Université d'Ottawa / University of Ottawa 2012
Subjects:
Online Access:http://hdl.handle.net/10393/20519
http://dx.doi.org/10.20381/ruor-5132