The Role of GLP Domains in Spreading of the G9a/GLP Complex and Regulation of the β-globin Gene Expression
Marked by a defect in the production of the Beta (β)-globin chain that make-up hemoglobin, Beta (β)-thalassemia is the most prevalent form of inherited single-gene disorders in the world. To understand the molecular mechanisms that govern the expression of the β-globin polypeptide encoded by the β-...
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| Language: | en |
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Université d'Ottawa / University of Ottawa
2012
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| Online Access: | http://hdl.handle.net/10393/22830 http://dx.doi.org/10.20381/ruor-3040 |