The Role of Scavenger Receptor-A in Heat Shock Protein 27-mediated Atheroprotection: Mechanistic Insights into a Novel Anti-atherogenic Therapy

The Role of Scavenger Receptor-A in Heat Shock Protein 27-mediated Atheroprotection: Mechanistic Insights into a Novel Anti-atherogenic Therapy

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Heat shock protein (HSP)27 is traditionally described as an intracellular chaperone and signaling molecule, but growing evidence suggests it is released from immune cells where it plays an anti-inflammatory role during atherogenesis. Previously, the O’Brien lab found that overexpression of HSP27 led...

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Bibliographic Details
Main Author: Raizman, Joshua E.
Other Authors: O'Brien, Edward
Language:en
Published: Université d'Ottawa / University of Ottawa 2012
Subjects:
scavenger receptor-A
heat shock protein 27
macrophage
foam cell formation
atherosclerosis
acetylated low density lipoprotein
NF-kappa b
Online Access:http://hdl.handle.net/10393/22836
http://dx.doi.org/10.20381/ruor-5733

Internet

http://hdl.handle.net/10393/22836
http://dx.doi.org/10.20381/ruor-5733

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