Phosphatidylcholine Metabolism and ACAT Affect the Trafficking of LDL-derived Free Cholesterol in Cholesterol-loaded CHO Cells

Phosphatidylcholine Metabolism and ACAT Affect the Trafficking of LDL-derived Free Cholesterol in Cholesterol-loaded CHO Cells

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In vitro studies have shown that the major membrane phospholipid phosphatidylcholine (PC) can positively influence the incorporation of cholesterol in lipid membranes. The influence of PC on the cellular trafficking of LDL-derived free cholesterol was investigated. Sterol regulatory-defective (SRD)-...

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Bibliographic Details
Main Author: Landry, Chandra
Other Authors: Lagace, Thomas
Language:en
Published: Université d'Ottawa / University of Ottawa 2012
Subjects:
Cholesterol
Filipin
NPC1
LDLR
Phosphatitylcholine
Lysosomal Loading
Lipid Droplet
Online Access:http://hdl.handle.net/10393/23087
http://dx.doi.org/10.20381/ruor-5892

Internet

http://hdl.handle.net/10393/23087
http://dx.doi.org/10.20381/ruor-5892

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