RNA Binding Protein HuR Regulates the Expression of Bcl-xL

RNA Binding Protein HuR Regulates the Expression of Bcl-xL

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The RNA-binding protein HuR controls key cellular processes by binding target mRNAs and regulating them at various post-transcriptional levels. HuR can function as an Internal Ribosome Entry Site (IRES) trans-acting factor that regulates the IRES-mediated translation of XIAP. Since XIAP and Bcl-xL e...

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Bibliographic Details
Main Author: Durie, Danielle
Other Authors: Holcik, Martin
Language:en
Published: Université d'Ottawa / University of Ottawa 2012
Subjects:
RNA binding protein
HuR
Bcl-xL
translation
IRES
Apoptosis
mitochondria
Online Access:http://hdl.handle.net/10393/23206
http://dx.doi.org/10.20381/ruor-3187

Internet

http://hdl.handle.net/10393/23206
http://dx.doi.org/10.20381/ruor-3187

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