Apolipoprotein E Isoforms Differentially Regulate Amyloid-β Stimulated Inflammation in Rat and Mouse Astrocytes
Neuroinflammation occurs in Alzheimer’s disease (AD) brain, and plays a role in neurodegeneration. The main aim of this study was to determine how treatments with exogenous apolipoprotein E (ApoE2, E3 and E4 isoforms), a genetic risk factor for AD, affects the amyloid-β (Aβ) induced inflammatory res...
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| Language: | en |
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Université d'Ottawa / University of Ottawa
2012
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| Online Access: | http://hdl.handle.net/10393/23581 http://dx.doi.org/10.20381/ruor-6258 |