Regulation of Neural Precursor Self-renewal via E2F3-dependent Transcriptional Control of EZH2
Our lab has recently found that E2F3, an essential cell cycle regulator, regulates the self-renewal capacity of neural precursor cells (NPCs) in the developing mouse brain. Chromatin immunoprecipitation (ChIP) and immunoblotting techniques revealed several E2F3 target genes, including the polycomb...
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Language: | en |
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Université d'Ottawa / University of Ottawa
2013
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Online Access: | http://hdl.handle.net/10393/23812 http://dx.doi.org/10.20381/ruor-6468 |