SHP-1/ Src Complex is a Master Regulator of the IL-12/IL-23 pro- and IL-10/IL-27 Anti-inflammatory Axis in TLR4-activated Signaling Pathways in Human Monocytes and Macrophages

Although the etiology surrounding many autoimmune diseases remains unknown, the underlying characteristic of many of these diseases is a disruption in the balance of pro- and anti- inflammatory cytokines It is well established that the dysregulation of the IL-12 family of cytokines, an increase in I...

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Bibliographic Details
Main Author: Konarski, Yulia
Other Authors: Kumar, Ashok
Language:en
Published: Université d'Ottawa / University of Ottawa 2013
Subjects:
Src
Online Access:http://hdl.handle.net/10393/25999
http://dx.doi.org/10.20381/ruor-3180