Regulation of cIAP1 mRNA Stability Through Its 3’ UTR by the RNA-Binding Protein HuR

The RNA-binding protein HuR is involved in numerous aspects of the RNA life-cycle. It is known for its ability to stabilize AU-Rich Element (ARE)-containing transcripts in the cytoplasm. The transcript of cIAP1, an important protein involved both in the regulation of apoptosis and NF-κB signaling, c...

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Bibliographic Details
Main Author: Liu, Peng
Other Authors: Holcik, Martin
Language:en
Published: Université d'Ottawa / University of Ottawa 2013
Subjects:
RNA
HuR
Online Access:http://hdl.handle.net/10393/26009
http://dx.doi.org/10.20381/ruor-4041