The Role of the Neuronal gap Junction Protein Connexin36 in Kainic Acid Induced Hippocampal Excitotoxicity

The Role of the Neuronal gap Junction Protein Connexin36 in Kainic Acid Induced Hippocampal Excitotoxicity

Kainic acid induced excitotoxicity causes pyramidal cell death in the CA3a/b region of the hippocampus. Electrical synapses, gap junctional communication, and single membrane channels in non-junctional membranes (hemichannels) composed of connexin36 (Cx36) have been implicated in both seizure propag...

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Bibliographic Details
Main Author: Akins, Mark S.
Other Authors: Bennett, Steffany
Language:en
Published: Université d'Ottawa / University of Ottawa 2014
Subjects:
Kainic acid
Excitotoxic injury
Excitotoxicity
Neuron
Neuronal survival
Connexin36
Connexin
Pyramidal cell
Interneuron
Hippocampus
Microglia
Neural protection
Seizure
Online Access:http://hdl.handle.net/10393/30392
http://dx.doi.org/10.20381/ruor-6778

Internet

http://hdl.handle.net/10393/30392
http://dx.doi.org/10.20381/ruor-6778

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