Catalysis via Induced Intramolecularity: Carbonyl-catalyzed Hydration of α-Amino Nitriles
In the last decade, there has been a surge of interest from the chemistry community in developing synthetic catalysts that emulate the remarkable rate accelerations observed for enzymatic reactions. One approach utilized by enzymes involves preorganization of substrate(s) using a favourable binding...
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| Language: | en |
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Université d'Ottawa / University of Ottawa
2014
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| Online Access: | http://hdl.handle.net/10393/31177 http://dx.doi.org/10.20381/ruor-3776 |