Phosphorylation of Filamin A by Cdk1/cyclin B1 Regulates Filamin A Subcellular Localization and is Important for Daughter Cell Separation

In cell culture, entry into mitosis of many adherent mammalian cells is accompanied by substantial changes in cellular architecture. Flat, spread-out interphase cells detach from the extracellular matrix and become more spherical. These changes in cell shape are mediated by rearrangements in the act...

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Bibliographic Details
Main Author: Szeto, Sandy
Other Authors: Lee, Jonathan
Language:en
Published: Université d'Ottawa / University of Ottawa 2014
Subjects:
Online Access:http://hdl.handle.net/10393/31732
http://dx.doi.org/10.20381/ruor-4047