Regulation of the Cellular Inhibitor of Apoptosis 1 (cIAP1) Translation by IRES Trans-Acting Factors and Impact on Cancer

Regulation of the Cellular Inhibitor of Apoptosis 1 (cIAP1) Translation by IRES Trans-Acting Factors and Impact on Cancer

Apoptosis is the mechanism by which complex multicellular organisms induce the programmed death of damaged cells, thus maintaining tissue homeostasis. One of the main hallmarks of cancer, apoptosis is tightly regulated by pro- and anti-apoptotic factors whose equilibrium will decide of the fate of t...

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Bibliographic Details
Main Author: Faye, Mame Daro
Other Authors: Holcik, Martin
Language:en
Published: Université d'Ottawa / University of Ottawa 2015
Subjects:
cIAP1
IGF2BP1
Translation
IRES
Cancer
Rhabdomyosarcoma
Apoptosis
Smac mimetics
NF45
immune modulators
Online Access:http://hdl.handle.net/10393/32007
http://dx.doi.org/10.20381/ruor-5757

Internet

http://hdl.handle.net/10393/32007
http://dx.doi.org/10.20381/ruor-5757

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