An Investigation of Sigma-1 Receptor Involvement in Glutamatergic Synaptic Physiology, Implications for Alzheimer’s Disease

The sigma-1 receptor (sig-1R) is a unique endoplasmic reticulum (ER) chaperone protein that interacts with a variety of voltage- and ligand-gated ion channels, which are components of an intricate system that regulates neuronal functioning. While there is an extensive body of knowledge pertaining to...

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Bibliographic Details
Main Author: McCann, Kieran
Other Authors: Bergeron, Richard
Language:en
Published: Université d'Ottawa / University of Ottawa 2015
Subjects:
Online Access:http://hdl.handle.net/10393/32344
http://dx.doi.org/10.20381/ruor-4300