Derivatization of Azomethine Imines into beta-Aminocarbonyl Motifs

β-Aminocarbonyl motifs are a privileged substructures in medicinal chemistry and peptidomimetics. As part of our efforts toward metal free aminations, we developed a method for intermolecular amino-carbonylation of alkenes using hydrazones. This method provides access to cyclic azomethine imines con...

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Bibliographic Details
Main Author: Betit, Lyanne
Other Authors: Beauchemin, André
Language:en
Published: Université d'Ottawa / University of Ottawa 2015
Subjects:
Online Access:http://hdl.handle.net/10393/32473
http://dx.doi.org/10.20381/ruor-4759