Interfacing Solid-State Nanopores with Gel Media to Slow DNA Translocations

One of the most crucial steps towards nanopore-based nucleic acid analysis is extending the dwell time of DNA molecules within the sensing region of the nanopore. I address this issue by interfacing solid-state nanopores with gel media, which sterically hinders translocating DNA molecules, increasin...

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Bibliographic Details
Main Author: Waugh, Matthew
Other Authors: Tabard-Cossa, Vincent
Language:en
Published: Université d'Ottawa / University of Ottawa 2015
Subjects:
Online Access:http://hdl.handle.net/10393/32774
http://dx.doi.org/10.20381/ruor-4183