The Effect of Freud-1/CC2D1A Knockout on EGF Receptor Activation
CC2D1A (coiled-coil and C2 domain containing protein 1A), also known as Freud-1, has been identified as a transcriptional repressor of the serotonin receptor 5-HT1A, a regulator of endosomal budding and an activator of NF-KB signaling. It also acts as a scaffold that promotes activity of the PI3K/Ak...
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Language: | en |
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Université d'Ottawa / University of Ottawa
2015
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Online Access: | http://hdl.handle.net/10393/33400 http://dx.doi.org/10.20381/ruor-4023 |