Kinome-wide RNAi Screening to Identify Kinases Involved in Post-translational Modification of FUS

Amyotrophic lateral sclerosis (ALS) is a devastating adult onset neurodegenerative disorder characterized by the selective degeneration of upper and lower motor neurons. Patients typically die from respiratory failures within 2-5 years after diagnosis. One of the milestones in ALS research is...

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Bibliographic Details
Main Author: Liu, Serena E. B.
Other Authors: Gray, Douglas
Language:en
Published: Université d'Ottawa / University of Ottawa 2016
Subjects:
FUS
ALS
Online Access:http://hdl.handle.net/10393/34199
http://dx.doi.org/10.20381/ruor-5322