Inactivation of Lgl1 in Glioblastoma
Glioblastoma is the most aggressive and invasive adult brain cancer. In glioblastoma, the loss of the tumour suppressor PTEN is the most common genetic alteration resulting in aberrant activation of the PI3-kinase pathway. In Drosophila, the loss of tumour suppressor Lgl results in massive overgrow...
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| Language: | en |
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Université d'Ottawa / University of Ottawa
2016
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| Online Access: | http://hdl.handle.net/10393/34965 http://dx.doi.org/10.20381/ruor-4972 |