Mutational Analysis to Define the Functional Role of the Third Intracellular Loop of D1-Class Dopaminergic Receptors

The third intracellular loop (IL3) and cytoplasmic tail (CT), which are the most divergent regions between human D1-class dopaminergic receptors (hD1R and hD5R), have been implicated in modulating their subtype-specific functional phenotypes. The importance of the IL3 for Guanine nucleotide-binding...

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Bibliographic Details
Main Author: Albaker, Awatif
Other Authors: Tiberi, Mario
Language:en
Published: Université d'Ottawa / University of Ottawa 2016
Subjects:
D1R
D5R
IL3
Online Access:http://hdl.handle.net/10393/35063
http://dx.doi.org/10.20381/ruor-5198