Non Parametric Unsupervised Clustering of ChIP Enrichment Regions Provides Isolation Vectors for Differential Functional Analysis

Gene transcription rates are influenced by proteins, known as Transcription Factors (TFs), that interact with DNA. The locations of TFs on the genome directly influence gene expression and the functional characteristics of a cell. TF binding locations can be estimated for entire genomes using high t...

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Bibliographic Details
Main Author: Griffith, Alexander
Other Authors: Perkins, Theodore
Language:en
Published: Université d'Ottawa / University of Ottawa 2016
Subjects:
R
PCA
Online Access:http://hdl.handle.net/10393/35084
http://dx.doi.org/10.20381/ruor-849