Reporter-based Synthetic Genetic Analysis of Budding Yeast Reveals Novel MMS-induced Effectors of the RNR3 Promoter

Reporter-based Synthetic Genetic Analysis of Budding Yeast Reveals Novel MMS-induced Effectors of the RNR3 Promoter

The DNA damage response is a cell-wide response that coordinates repair and cell-cycle progression. Crucial to fidelity of genetic propagation, survival, and apoptosis, dysfunctions in the response are at the root of genome instability syndromes and cancer predisposition in mammalian cells. Within t...

Full description

Bibliographic Details
Main Author: Elnour, Nada
Other Authors: Kaern, Mads
Format: Others
Language:en
Published: Université d'Ottawa / University of Ottawa 2016
Subjects:
Reporter synthetic genetic array
Flow cytometry
RNR3 promoter
DNA damage response
High-throughput screen
Methyl methanesulfonate
Differential EMAP
Chemogenetic screen
Online Access:http://hdl.handle.net/10393/35143
http://dx.doi.org/10.20381/ruor-853

Internet

http://hdl.handle.net/10393/35143
http://dx.doi.org/10.20381/ruor-853

Similar Items