Polycomb-like 2 (Mtf2/Pcl2) is Required for Epigenetic Regulation of Hematopoiesis

Polycomb proteins are epigenetic regulators that are critical in mediating gene repression at critical stages during development. Core and accessory proteins make up the Polycomb Repressive Complex 2 (PRC2), which is responsible for trimethylation of lysine 27 on histone 3 (H3K27me3), leading to mai...

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Bibliographic Details
Main Author: Rothberg, Janet L.
Other Authors: Stanford, William
Language:en
Published: Université d'Ottawa / University of Ottawa 2016
Subjects:
Online Access:http://hdl.handle.net/10393/35323
http://dx.doi.org/10.20381/ruor-281