The Role of Transmembrane Domain Helix-Helix Interactions in the Function of Pentameric Ligand-Gated Ion Channels

The pentameric ligand gated ion channel super family plays a central role in fast synaptic communication between neurons and at the neuromuscular junction. Extensive studies on the prototypic pLGIC, the Torpedo nicotinic acetylcholine receptor (nAChR) have revealed an exquisite lipid sensitivity, wi...

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Bibliographic Details
Main Author: Therien, James Patrick Daniel
Other Authors: Baenziger, John E.
Language:en
Published: Université d'Ottawa / University of Ottawa 2017
Subjects:
Online Access:http://hdl.handle.net/10393/35643
http://dx.doi.org/10.20381/ruor-600