Dissection of TLR4-Induced Necroptosis Using Specific Inhibitors of Endocytosis and P38 MAPK
Necroptosis is a pathway of inflammatory cell death that is associated with several pathologies and is induced by ligation of surface TLR or cytokine receptors in macrophages. Many signaling pathways depend on endocytosis, a process mediated by GTPases such as dynamin. We evaluated the role of dynam...
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| Format: | Others |
| Language: | en |
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Université d'Ottawa / University of Ottawa
2017
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| Online Access: | http://hdl.handle.net/10393/35968 http://dx.doi.org/10.20381/ruor-20249 |