Functional Analysis of Zebrafish Paralogs, parla and parlb, by CRISPR-Cas9 Mediated Mutagenesis

Parkinson’s disease is a highly prevalent multifactorial neurodegenerative disorder caused by a complex cascade of interactions between various genetic and environmental factors. Due to this, the majority of cases are termed idiopathic. However, about 10% of PD cases are due to defined genetic facto...

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Bibliographic Details
Main Author: Jung, Megan
Other Authors: Ekker, Marc
Language:en
Published: Université d'Ottawa / University of Ottawa 2017
Subjects:
Online Access:http://hdl.handle.net/10393/36478
http://dx.doi.org/10.20381/ruor-20758