Structural and Biochemical Insights into the Assembly of the DPY-30/Ash2L Heterotrimer
In eukaryotes, the SET1 family of methyltransferases carry out the methylation of Lysine 4 on Histone H3. Alone, these enzymes exhibit low enzymatic activity and require the presence of additional regulatory proteins, which include RbBP5, Ash2L, WDR5 and DPY-30, to stimulate their catalytic activity...
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| Format: | Others |
| Language: | en |
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Université d'Ottawa / University of Ottawa
2017
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| Online Access: | http://hdl.handle.net/10393/36616 http://dx.doi.org/10.20381/ruor-20896 |