Forced Overexpression of Translationally Controlled Tumor Protein (TCTP/TPT1) Induces a Growth-Dysregulated Phenotype in Endothelial and Smooth Muscle Cells: Role of TCTP Exosomal Export in Paracrine Cell-Cell Signaling Induced by Endothelial Injury
Background: Pulmonary arterial hypertension (PAH) is a lethal disease for which the fundamental molecular mechanisms are only partially understood. Existing therapies, which primarily focus on endothelial dysfunction, have limited effects on improving outcomes. Increases in pulmonary vascular resist...
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| Format: | Others |
| Language: | en |
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Université d'Ottawa / University of Ottawa
2019
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| Online Access: | http://hdl.handle.net/10393/38674 http://dx.doi.org/10.20381/ruor-22926 |