The Regulation of PCSK9 Structure and Function Through Lipoprotein Interactions

Proprotein convertase subtilisin / kexin type 9 (PCSK9) is a negative regulator of the low-density lipoprotein receptor, and PCSK9 inhibition has become an important cholesterol-lowering therapeutic strategy. PCSK9 also associates with LDL particles, and evidence suggests that the activity of PCSK9...

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Bibliographic Details
Main Author: Sarkar, Samantha Khadija
Other Authors: Lagace, Thomas
Format: Others
Language:en
Published: Université d'Ottawa / University of Ottawa 2019
Subjects:
LDL
IDL
Online Access:http://hdl.handle.net/10393/39099
http://dx.doi.org/10.20381/ruor-23347