Discovery and Application of Neoepitopes in an Oncolytic Rhabdovirus Vaccine Approach to Treat Glioblastoma Multiforme

Glioblastoma multiforme is the most common and lethal primary brain tumour in adults. Its aggressive and invasive phenotype makes it resistant to current standards of care, with a patient median survival following treatment of only 14 months. Potent and safe therapeutics are necessary to improve pat...

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Bibliographic Details
Main Author: Jilesen, Zachary Keavin
Other Authors: Stojdl, David
Format: Others
Language:en
Published: Université d'Ottawa / University of Ottawa 2019
Subjects:
GBM
Online Access:http://hdl.handle.net/10393/39688
http://dx.doi.org/10.20381/ruor-23931