TGFβ Causes Postoperative Natural Killer Cell Paralysis Through mTOR Inhibition
Background: Life-prolonging tumour removal surgery is associated with increased metastasis and disease recurrence. Natural Killer (NK) cells are critical for the anti-tumour immune response. Postoperatively, NK cell cytotoxicity and interferon-gamma (IFNγ) production are profoundly suppressed and th...
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Others |
| Language: | en |
| Published: |
Université d'Ottawa / University of Ottawa
2020
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/10393/40945 http://dx.doi.org/10.20381/ruor-25171 |