Autotaxin promotes cancer cell invasion via the lysophosphatidic acid receptor 4

Tumor metastasis is a fundamental property of malignant cancer cells and the major cause of death in cancer patients. Recent studies indicate that tumor cell invasion and metastasis may be initiated by the formation of the actin-rich cell protrusions with ECM degradation activity, invadopodia. Howev...

Full description

Bibliographic Details
Main Author: Harper, Kelly
Other Authors: Dubois, Claire
Language:English
Published: Université de Sherbrooke 2010
Subjects:
Online Access:http://savoirs.usherbrooke.ca/handle/11143/4035