Importance of dimerization in aggregation and neurotoxicity of Prion and [alpha]-Synuclein in prion and Parkinson's diseases

Abstract: Neurodegenerative diseases are associated with progressive loss of structure or function of neurons which results in cell death. Recent evidence indicate that all neurodegenerative disorders, sporadic or transmissible, may have a common pathological mechanism at the molecular level. This c...

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Bibliographic Details
Main Author: Roostaee, Alireza
Other Authors: Roucou, Xavier
Language:English
Published: Université de Sherbrooke 2015
Subjects:
PD
Fv
Online Access:http://hdl.handle.net/11143/6650