Exploring the selectivity of metal ions in the active site of the enzyme superoxide dismutase (SOD) using site-directed mutagenesis

Exploring the selectivity of metal ions in the active site of the enzyme superoxide dismutase (SOD) using site-directed mutagenesis

Iron/Manganese superoxide dismutases (Fe/Mn-SODs) are metalloenzymes with highly conserved protein folds, active sites, and dimer interfaces. They protect cells against oxidative stress by catalyzing the conversion of the cytotoxic free radical superoxide to molecular oxygen and hydrogen peroxide. T...

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Bibliographic Details
Main Author: Rengifo, Emérita Mendoza
Other Authors: Garratt, Richard Charles
Format: Others
Language:en
Published: Biblioteca Digitais de Teses e Dissertações da USP 2016
Subjects:
Atividade enzimática
Catalytic metals
Cristalografia
Crystallography
Enzymatic activity
Metais catalíticas
Superoxide dismutase
Superóxido dismutases
Online Access:http://www.teses.usp.br/teses/disponiveis/76/76132/tde-05012017-114055/

Internet

http://www.teses.usp.br/teses/disponiveis/76/76132/tde-05012017-114055/

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