Monomeric states of the beta-amyloid peptide investigated under high pressure by nuclear magnetic resonance spectroscopy

The main histological feature of Alzheimer\'s disease is the presence of amyloid plaques in the patient\'s brain. The most abundant element of these plaques is the β-amyloid peptide (Aβ). Initially soluble, the peptide exhibits in solution an intricate equilibrium among m...

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Bibliographic Details
Main Author: Cavini, Ítalo Augusto
Other Authors: Garratt, Richard Charles
Format: Others
Language:en
Published: Biblioteca Digitais de Teses e Dissertações da USP 2018
Subjects:
Online Access:http://www.teses.usp.br/teses/disponiveis/76/76132/tde-07052019-102916/