Droplet interface bilayers: microfluidic methods to model pharmacokinetics in artificial cell membranes
Modern drug development is an astronomically expensive and time consuming undertaking. Because of this, studying the pharmacokinetic properties of drugs in vitro has become an integral step early in the process of drug development, with the goal of preventing costly failures late in the process, and...
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Language: | English en |
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2021
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Online Access: | http://hdl.handle.net/1828/13401 Korner, J. L.; Stephenson, E. B.; Elvira, K. S. A Bespoke Microfluidic Pharmacokinetic Compartment Model for Drug Absorption Using Artificial Cell Membranes. Lab Chip 2020, 20 (11), 1898–1906. https://doi.org/10.1039/D0LC00263A Stephenson, E. B.; Elvira, K. S. Biomimetic Artificial Cells to Model the Effect of Membrane Asymmetry on Chemoresistance. Chem. Commun. 2021, 57 (53), 6534–6537. https://doi.org/10.1039/D1CC02043A |
Internet
http://hdl.handle.net/1828/13401Korner, J. L.; Stephenson, E. B.; Elvira, K. S. A Bespoke Microfluidic Pharmacokinetic Compartment Model for Drug Absorption Using Artificial Cell Membranes. Lab Chip 2020, 20 (11), 1898–1906. https://doi.org/10.1039/D0LC00263A
Stephenson, E. B.; Elvira, K. S. Biomimetic Artificial Cells to Model the Effect of Membrane Asymmetry on Chemoresistance. Chem. Commun. 2021, 57 (53), 6534–6537. https://doi.org/10.1039/D1CC02043A