A Loss of the Fragile X mental retardation protein alters the spatial and temporal expression of glutamate receptors in the mouse brain
Fragile X Syndrome (FXS) is the leading cause of inherited intellectual disability. The disorder is caused by a trinucleotide expansion that silences the Fragile X Mental Retardation 1 (Fmr1) gene resulting in the loss of its protein product, the Fragile X Mental Retardation Protein (FMRP). FXS pati...
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Language: | English en |
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2012
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Online Access: | http://hdl.handle.net/1828/4372 |