Structural Insights into Antibodies Specific for Bacterial Lipopolysaccharide Core and Development of Protein Electron Crystallography Techniques

Structural Insights into Antibodies Specific for Bacterial Lipopolysaccharide Core and Development of Protein Electron Crystallography Techniques

Lipopolysaccharide (LPS), one of the main components of Gram-negative bacterial cell walls, is a potent endotoxin. Structures of the unique protective monoclonal antibody (mAb) WN1 222-5 in complex with Escherichia coli R2 and R4 LPS core regions show that recognition occurs in a manner similar to t...

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Bibliographic Details
Main Author: Gomery, Kathryn
Other Authors: Evans, S. V.
Language:English
en
Published: 2013
Subjects:
Antibodies
Lipopolysaccharide
Structural Biology
Electron Crystallography
Carbohydrates
Septic Shock
Online Access:http://hdl.handle.net/1828/4816

Internet

http://hdl.handle.net/1828/4816

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