Purification and Uptake Studies of Recombinant Human N-α-D-Acetylglucosaminidase from Sf9 Insect Cells
Human α-N-acetylglucosaminidase (Naglu) is a lysosomal enzyme implicated in the rare metabolic storage disorder Mucopolysaccharidosis III type B (MPS IIIB). A deficiency in Naglu results in a buildup of heparan sulfate in lysosomes, which is most detrimental in the central nervous system, causing me...
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| Language: | English en |
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2015
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| Online Access: | http://hdl.handle.net/1828/6583 |