Synthetic temperature inducible lethal genetic circuits in Escherichia coli

Temperature-sensitivity (TS) is often used as a way to attenuate microorganisms to convert them into live vaccines. Studies indicate that live vaccines are often necessary for the complete clearance of certain pathogenic organisms. In this work we explore the use of TS genetic circuits that express...

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Bibliographic Details
Main Author: Pearce, Stephanie
Other Authors: Nano, Francis E.
Format: Others
Language:English
en
Published: 2016
Subjects:
Online Access:http://hdl.handle.net/1828/7503