The S. Cerevisiae Rho GTPase Cdc42p Is Spatially Regulated by Complex Formation with its GDI Rdi1p and Localization of its GEF Cdc24p

The S. cerevisisae Rho GTPase Cdc42p localizes around the entire plasma membrane, but is only activated at sites of polarized growth in a cell cycle-dependent manner. This spatial and temporal control ensures that Cdc42p is inactive within the cytoplasm and outside of the polarized cortical domain,...

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Bibliographic Details
Main Author: Cole, karen
Format: Others
Published: ScholarWorks @ UVM 2008
Subjects:
Online Access:http://scholarworks.uvm.edu/graddis/50
http://scholarworks.uvm.edu/cgi/viewcontent.cgi?article=1049&context=graddis