Characterizing the Roles of BRAF, PTEN and Cdkn2a in Novel Mouse Models of Melanoma Formation and Progression
There will be an estimated 60,000 new cases and nearly 8000 deaths in the US this year due to malignant melanoma. People living in the US are expected to have a 1 in 71 lifetime risk of developing the disease. Activating mutations in BRAF occur in approximately 60% of melanomas and in 80% of beni...
| Main Author: | |
|---|---|
| Format: | Others |
| Published: |
ScholarWorks @ UVM
2008
|
| Subjects: | |
| Online Access: | http://scholarworks.uvm.edu/graddis/62 http://scholarworks.uvm.edu/cgi/viewcontent.cgi?article=1061&context=graddis |