Effects of Erythropoietin and Glycogen Synthase Kinase 3 on Hypoxia Inducable Factor-1α
Cancerous tumors adjust their signaling pathways to facilitate survival in a hypoxic environment. The pro-angiogenic transcription factor hypoxia inducible factor -1α (HIF-1α) is stabilized in hypoxia and promotes tumor cell survival, proliferation, and metastasis by inducing transcription of many t...
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| Format: | Others |
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ScholarWorks @ UVM
2008
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| Online Access: | http://scholarworks.uvm.edu/graddis/100 http://scholarworks.uvm.edu/cgi/viewcontent.cgi?article=1099&context=graddis |