Fluctuations and Instantons in Complex Landscapes: From Ligand Unbinding to Proton Transfer
Biophysical entities are complex systems systems with strong environmental coupling, dominated by fluctuations on a hierarchy of timescales. These properties confound simulation of ligand binding and catalysis, inflating the scale of the problem to one tractable only with a considerable outlay of r...
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VCU Scholars Compass
2011
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| Online Access: | http://scholarscompass.vcu.edu/etd/281 http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=1280&context=etd |