Identification and Quantification of Protein Carbonylation by Mass Spectrometry
Accumulated evidence indicates oxidative stress plays important roles in disease and aging. Under oxidative stress, lipid peroxidation (LPO) leads to reactive carbonyl species (RCS) that can modify a wide range of biomolecules including protein, DNA and carbohydrate. In this dissertation, we investi...
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VCU Scholars Compass
2012
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Online Access: | http://scholarscompass.vcu.edu/etd/321 http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=1320&context=etd |