The role of Fyn and B-cell expressed ADAM10 in early B cell development, germinal center formation and terminal B cell differentiation

In these studies we sought to determine the role of Fyn kinase and ADAM10 in B cell biology. A disintegrin and metalloproteinase 10 (ADAM10) is a zinc dependent proteinase related to matrix metalloproteinases. ADAM10 has emerged as a key regulator of cellular processes by cleaving and shedding extra...

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Bibliographic Details
Main Author: Chaimowitz, Natalia
Format: Others
Published: VCU Scholars Compass 2012
Subjects:
Online Access:http://scholarscompass.vcu.edu/etd/374
http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=1373&context=etd