THC-MEDIATED INDUCTION OF ΔFOSB AND ITS MODULATION OF CB1R SIGNALING AND ADAPTATION
The main psychoactive and therapeutic effects of Δ9-tetrahydrocannabinol (THC) are mediated through cannabinoid type 1 receptors (CB1Rs). The therapeutic uses of THC are mitigated by the development of tolerance to these therapeutic effects, whereas tolerance does not readily develop to some of the...
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| Format: | Others |
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VCU Scholars Compass
2013
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| Online Access: | http://scholarscompass.vcu.edu/etd/550 http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=1549&context=etd |