Synthetic, Sulfated, Lignin-Based Anticoagulants
Chemoenzymatically synthesized low molecular weight lignin polymers have been previously found to be potent inhibitors of a number of serine proteases via allosteric mechanisms targeting heparin binding sites. Herein, we describe the creation of synthetic sulfated β-O4 lignin (SbO4L) polymer, which...
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VCU Scholars Compass
2014
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| Online Access: | http://scholarscompass.vcu.edu/etd/598 http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=1597&context=etd |