Interleukin-10 Induces Apoptosis in Developing Mast Cells via a Mitochondrial, STAT3-dependent Pathway

Objective. The aim of this study was to determine the effects of interleukin-10 on mast cell development from bone marrow progenitors.Materials and Methods. Unseparated mouse bone marrow cells were cultured in IL-3+SCF, giving rise to mast cells and monocytes/macrophages. The addition of IL-10, an...

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Bibliographic Details
Main Author: Bailey, Daniel Paul
Format: Others
Published: VCU Scholars Compass 2005
Subjects:
Online Access:http://scholarscompass.vcu.edu/etd/1410
http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=2409&context=etd